Week 13 has delivered multiple memorable moments around the league, and the Buffalo Bills and San Francisco 49ers are looking to put their stamp on one in the final game of Sunday’s action. Highmark Stadium in Orchard Park, New York, was blanketed by snow over the weekend, but things should be clear for the game.
The Bills return from their bye and will look to keep pace with the Kansas City Chiefs at the top of the AFC. Josh Allen has Buffalo humming, winning six consecutive games while scoring 30 points or more in five straight. The Bills can secure their fifth consecutive AFC East crown with a win on “Sunday Night Football.”
The visiting 49ers come into this showdown with a 5-6 record. For the first time since 2020, the defending NFC champs have a losing record this late in the season. Running back Christian McCaffrey will play in his fourth game after missing the first two months of the season and will look to make an impact against a Bills defense tied with the fourth-highest yards per carry allowed entering Week 13.
Quarterback Brock Purdy is expected to return under center for the Niners after he missed last week’s game against the Green Bay Packers with a right shoulder injury. The Bills have afforded themselves a cushion in the AFC East, but the 49ers find themselves with their backs against the wall with six games remaining in the regular season.
USA TODAY Sports will provide live updates, highlights and more from the “Sunday Night Football” matchup between the Bills and 49ers below. All times are Eastern.
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The Bills and 49ers game will wrap up Sundays Week 13 of the 2024 NFL season with “Sunday Night Football” at 8:20 p.m. ET. 
Here’s how the USA TODAY Sports staff feels the Week 13 “SNF” matchup between the Bills and 49ers will shape up: 
According to the Weather Channel, it’s going to be a cold night in Orchard Park with a high of 30 degrees at kickoff and a low of 29 degrees at midnight. The good news, the wind will not be much of a factor with gusts topping out at 10 MPH. There is a slight chance of snow showers with little to no accumulation.
For cord cutters looking for a live stream for the matchup, you can turn to Fubo TV. Fubo TV carries NBC, as well as CBS, FOX, NFL Network and the ESPN family of networks, meaning you can catch NFL action through the remainder of the season. 
Peacock, the proprietary streaming service of NBC, will also carry the game. 
The Bills are favorites to defeat the 49ers, according to the BetMGM NFL odds. Not interested in this game? Check out expert picks and best bets for every NFL game this week.   
Mack Hollins is walking in a winter wonderland, barefoot.
The Buffalo Bills receiver seemingly isn’t worried about the cold, especially as over a foot of snow is dumped on the region. Hollins donned some all-white attire ahead of the “Sunday Night Football” game against the 49ers. Without socks or shoes, the receiver walked through the shoveled parking lot, although the pavement was likely freezing. — Nick Brinkerhoff
These interconference opponents have met 13 times in NFL history. The Bills lead the matchup all-time with a 7-6 record.  
The most recent meeting between these teams was in December 2020 when the Bills won in impressive fashion on the road. Josh Allen threw for 375 yards and tossed four touchdown passes as the Bills stayed in sole possession of first place in the AFC East at the time.
During the 1992 season, the 49ers and Bills had a memorable, high-scoring encounter in which there was more than 1,000 yards of offense and no punts. The Bills won the game, 34-31.
The New England Patriots and Pittsburgh Steelers are tied for the most Super Bowl wins with six. 
Pittsburgh and Dallas have the unique distinction of playing each other more than any other team combination in Super Bowl history with three matchups. 
The 49ers have eight total Super Bowl appearances and five rings to show for it, the most recent coming during the 1994 season in Super Bowl XXIX. The Bills have four Super Bowl appearances, which came in consecutive seasons in 1990-93, but no victories.
NFL franchises with most Super Bowl wins:
➤ Super Bowl winners: All-time scores, results for NFL title game
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